“The big puzzle is why species like humans have not gone extinct if we have been around for tens of thousands of years as evolutionists maintain.1 In a complex organism, a high mutation rate combined with a low reproduction rate makes it very difficult for ‘natural selection’ to remove deleterious mutations from the population.
…in these more-complicated systems, there are more things that can go wrong, i.e. more machinery that can be broken.2”
See more detail here: https://creation.com/genetic-entropy-and-simple-organisms