“More recently, Eugene Koonin and others tried to calculate the bare minimum required for a living cell, and came up with a result of 256 genes. But they were doubtful whether such a hypothetical bug could survive, because such an organism could barely repair DNA damage, could no longer fine-tune the ability of its remaining genes, would lack the ability to digest complex compounds, and would need a comprehensive supply of organic nutrients in its environment.4
Yet even this ‘simple’ organism has far too much information to be expected from time and chance, without natural selection. The information theorist Hubert Yockey calculated that given a pool of pure, activated biological amino acids, the total amount of information which could be produced, even allowing 109 years as evolutionists posit, would be only a single small polypeptide 49 amino acid residues long.5 This is about 1/8 the size (therefore information content) of a typical protein, yet the hypothetical simple cell above needs at least 256 proteins. And Yockey’s estimate generously presupposes that the many chemical hurdles can be overcome, which is a huge assumption, as shown by many creationist writers.6”
Read more from here: https://creation.com/how-simple-can-life-be
